Comments on: No Worries: Pfizer Still Hides Bad Lipitor Data, But Has More Good Data For You Today http://www.pharmalot.com/2007/06/pfizer-still-hides-bad-data-touts-more-good-data/ News, Comment and Conversation Fri, 10 Feb 2012 21:08:35 +0000 http://wordpress.org/?v=2.6.2 By: Ed http://www.pharmalot.com/2007/06/pfizer-still-hides-bad-data-touts-more-good-data/#comment-13892 Ed Mon, 25 Jun 2007 22:01:07 +0000 http://www.pharmalot.com/2007/06/pfizer-still-hides-bad-data-touts-more-good-data/#comment-13892 How many doctors actually use 80mg of Lipitor? ANd is it "Lipitor" or the lowering of the ldl that reduces events? Isn't there some NEW warning in Lipitors PI about the 80mg dose and MI patients? How many doctors actually use 80mg of Lipitor? ANd is it “Lipitor” or the lowering of the ldl that reduces events? Isn’t there some NEW warning in Lipitors PI about the 80mg dose and MI patients?

]]> By: Hank http://www.pharmalot.com/2007/06/pfizer-still-hides-bad-data-touts-more-good-data/#comment-13859 Hank Mon, 25 Jun 2007 18:22:36 +0000 http://www.pharmalot.com/2007/06/pfizer-still-hides-bad-data-touts-more-good-data/#comment-13859 I certainly concur with the big point - that Pfizer should not continue to "closet" (kindest word) the numbers from the SEC-related study that undid the initial hype. In the meantime, all these announcements are frustrating because they leave out NNT numbers and absolute risk differences. Considering how often Lipitor is touted as a "miracle drug" - and the latest study was for secondary prevention at the highest Lipitor dose that is given, 80 mg, the ideal circumstances for miracles to reveal themselves - how impressive are the relative risk differences is in the mind of the beholder. In the meantime, as a kind of aside in the latest report, the risk of hemorrhagic stroke was actually _increased_ relative to placebo among patients taking Lipitor. But no numbers are provided on this difference, not even relative risk ones. Makes one kinda wonder. I certainly concur with the big point - that Pfizer should not continue to “closet” (kindest word) the numbers from the SEC-related study that undid the initial hype.

In the meantime, all these announcements are frustrating because they leave out NNT numbers and absolute risk differences. Considering how often Lipitor is touted as a “miracle drug” - and the latest study was for secondary prevention at the highest Lipitor dose that is given, 80 mg, the ideal circumstances for miracles to reveal themselves - how impressive are the relative risk differences is in the mind of the beholder.

In the meantime, as a kind of aside in the latest report, the risk of hemorrhagic stroke was actually _increased_ relative to placebo among patients taking Lipitor. But no numbers are provided on this difference, not even relative risk ones.

Makes one kinda wonder.

]]> By: JS http://www.pharmalot.com/2007/06/pfizer-still-hides-bad-data-touts-more-good-data/#comment-13845 JS Mon, 25 Jun 2007 15:27:34 +0000 http://www.pharmalot.com/2007/06/pfizer-still-hides-bad-data-touts-more-good-data/#comment-13845 how can we believe anything they say...duh they are so incredibly not credible how can we believe anything they say…duh they are so incredibly not credible

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