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	<title>Comments on: Inhaled Insulin: A Giant Step For MannKind?</title>
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	<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/</link>
	<description>News, Comment and Conversation</description>
	<pubDate>Fri, 10 Feb 2012 21:22:11 +0000</pubDate>
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		<title>By: Janice</title>
		<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-119102</link>
		<dc:creator>Janice</dc:creator>
		<pubDate>Tue, 29 Jan 2008 06:01:35 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-119102</guid>
		<description>Try checking out www.exubera.com for an update. P. announced Jan. 16, 2008, that if your doctor fills out the paperwork you can get Exubera for another 6 months at no charge--more time to switch to other medicines.</description>
		<content:encoded><![CDATA[<p>Try checking out <a href="http://www.exubera.com" rel="nofollow">http://www.exubera.com</a> for an update. P. announced Jan. 16, 2008, that if your doctor fills out the paperwork you can get Exubera for another 6 months at no charge&#8211;more time to switch to other medicines.</p>
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		<title>By: Geoff</title>
		<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-100095</link>
		<dc:creator>Geoff</dc:creator>
		<pubDate>Thu, 17 Jan 2008 02:17:34 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-100095</guid>
		<description>Wow! I remember when... "pork" insulin! I was diagnosed in 84. I was on Exubera for about 8 months. During that time, my 14 year old son was diagnosed as well. I wished he had an opportunity to give Exubera a try. He is currently on three injections a day. I didn't mind so bad for myself about going back to injections, but seeing a loved one, newly diagnosed and struggling is so different. I have enough Exubera to make it another month. I hope something hits the pharmacy soon. I agree that Exubera was poorly marketed. After using both options...you can bet I will toot a horn loudly for the inhaled insulins. Information is so hard to acquire. Has anyone heard anything about any "projected" release dates for new stuff?</description>
		<content:encoded><![CDATA[<p>Wow! I remember when&#8230; &#8220;pork&#8221; insulin! I was diagnosed in 84. I was on Exubera for about 8 months. During that time, my 14 year old son was diagnosed as well. I wished he had an opportunity to give Exubera a try. He is currently on three injections a day. I didn&#8217;t mind so bad for myself about going back to injections, but seeing a loved one, newly diagnosed and struggling is so different. I have enough Exubera to make it another month. I hope something hits the pharmacy soon. I agree that Exubera was poorly marketed. After using both options&#8230;you can bet I will toot a horn loudly for the inhaled insulins. Information is so hard to acquire. Has anyone heard anything about any &#8220;projected&#8221; release dates for new stuff?</p>
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		<title>By: Laureen</title>
		<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-47244</link>
		<dc:creator>Laureen</dc:creator>
		<pubDate>Wed, 19 Dec 2007 13:02:48 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-47244</guid>
		<description>Exubera isn't burried yet.  I am confident someone (maybe Nektar) will produce it.  The production facility already exists and new, smaller inhalers were in the pipeline for 2008.  I have bene on Exubera for 9 months and it is the most wonderful non-invasive option for Type 1 diabetics.  I went from taking 4 injections a day to one and don't want to go back to 4.  Keep the faith and keep the focus alive on it.  the more media attention, the more someone will pick it up.  
Oh an Pfizer failed because they don't know how to market insulin to endocrinologists, nor did they have a LONG term strategy, not because Exubera isn't as good as injectible insulin.</description>
		<content:encoded><![CDATA[<p>Exubera isn&#8217;t burried yet.  I am confident someone (maybe Nektar) will produce it.  The production facility already exists and new, smaller inhalers were in the pipeline for 2008.  I have bene on Exubera for 9 months and it is the most wonderful non-invasive option for Type 1 diabetics.  I went from taking 4 injections a day to one and don&#8217;t want to go back to 4.  Keep the faith and keep the focus alive on it.  the more media attention, the more someone will pick it up.<br />
Oh an Pfizer failed because they don&#8217;t know how to market insulin to endocrinologists, nor did they have a LONG term strategy, not because Exubera isn&#8217;t as good as injectible insulin.</p>
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		<title>By: Melody</title>
		<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-34888</link>
		<dc:creator>Melody</dc:creator>
		<pubDate>Mon, 10 Dec 2007 16:35:33 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-34888</guid>
		<description>Todd--

I've never claimed that animal insulin was the best product in the world, only that those who find that they can't survive on rDNA, or who have a better quality of life using animal products should have freedom of choice. This has been denied them by the "capitalist market" you so enthusiastically support. 

You state that when there is no demand, there is no product. But as we continue to see reported, market leaders can manipulate numbers so well that Orwellian double-speak prevails . . . white is black and good is bad. There was both demand and NEED for products that were systematically withdrawn from the market under the guise of 'business decisions' and 'declining market share.' When doctors were told that the removal of animal insulins would become reality, they could either switch their patients 'now or later.' Those who chose the former were instrumental in shifting market numbers, creating a self-fulfilling model. This was nothing more than skillful market manipulation . . . by a corporation who chose to exercise power BECAUSE IT COULD.</description>
		<content:encoded><![CDATA[<p>Todd&#8211;</p>
<p>I&#8217;ve never claimed that animal insulin was the best product in the world, only that those who find that they can&#8217;t survive on rDNA, or who have a better quality of life using animal products should have freedom of choice. This has been denied them by the &#8220;capitalist market&#8221; you so enthusiastically support. </p>
<p>You state that when there is no demand, there is no product. But as we continue to see reported, market leaders can manipulate numbers so well that Orwellian double-speak prevails . . . white is black and good is bad. There was both demand and NEED for products that were systematically withdrawn from the market under the guise of &#8216;business decisions&#8217; and &#8216;declining market share.&#8217; When doctors were told that the removal of animal insulins would become reality, they could either switch their patients &#8216;now or later.&#8217; Those who chose the former were instrumental in shifting market numbers, creating a self-fulfilling model. This was nothing more than skillful market manipulation . . . by a corporation who chose to exercise power BECAUSE IT COULD.</p>
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		<title>By: TOdd</title>
		<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-34763</link>
		<dc:creator>TOdd</dc:creator>
		<pubDate>Mon, 10 Dec 2007 15:03:52 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-34763</guid>
		<description>just wanted to beat you to the punch.  So he has been on animal insulin and doesn't think that is the best thing in the world - huh, that can't be right.

And if you think a company should burn through $1 billion dollars a year so 2000 people can benefit from a drug that could be replaced with shots --- you and I have different views of what a capitalist society is.  Now if this was a life saving product it is a different arguement.  As you have found out, when there is no demand, there is no product.

no interest in Lilly, or any other company.  sold all my stock - there are better places to be in the market right now.</description>
		<content:encoded><![CDATA[<p>just wanted to beat you to the punch.  So he has been on animal insulin and doesn&#8217;t think that is the best thing in the world - huh, that can&#8217;t be right.</p>
<p>And if you think a company should burn through $1 billion dollars a year so 2000 people can benefit from a drug that could be replaced with shots &#8212; you and I have different views of what a capitalist society is.  Now if this was a life saving product it is a different arguement.  As you have found out, when there is no demand, there is no product.</p>
<p>no interest in Lilly, or any other company.  sold all my stock - there are better places to be in the market right now.</p>
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		<title>By: Melody</title>
		<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-34603</link>
		<dc:creator>Melody</dc:creator>
		<pubDate>Mon, 10 Dec 2007 13:29:37 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-34603</guid>
		<description>Todd--Your ad hominem argument suggests that you have a vested interest in Lilly. Do you work for them . . . or merely get paid for "attacking the messenger" as you troll through healthcare/pharma blogs? BTW, your ignorance is showing; if Dennis has had diabetes for 60 years, he has already used animal insulin. He has just discovered that big pharma views patients as merely commodities with purse-strings.

Dennis--Sorry you have discovered that "freedom of choice" is well-trumped by pharma's "market economy" and blockbuster mentality.</description>
		<content:encoded><![CDATA[<p>Todd&#8211;Your ad hominem argument suggests that you have a vested interest in Lilly. Do you work for them . . . or merely get paid for &#8220;attacking the messenger&#8221; as you troll through healthcare/pharma blogs? BTW, your ignorance is showing; if Dennis has had diabetes for 60 years, he has already used animal insulin. He has just discovered that big pharma views patients as merely commodities with purse-strings.</p>
<p>Dennis&#8211;Sorry you have discovered that &#8220;freedom of choice&#8221; is well-trumped by pharma&#8217;s &#8220;market economy&#8221; and blockbuster mentality.</p>
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		<title>By: TOdd</title>
		<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-33965</link>
		<dc:creator>TOdd</dc:creator>
		<pubDate>Mon, 10 Dec 2007 03:13:13 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-33965</guid>
		<description>Have you tried animal insulins.  I believe there might be someone on this site that will tell you Lilly forced Exubra off the market along with animal insulins years ago.  Blame Lilly.

But seriously, it is a shame this med was taken off the market - but that is the market economy we live in.  Pfizer spent billions and I believe they were selling about $20 million/qtr.  Pfizer is a big company, but no one can lose $1billion/year for a disease that is still treatable with traditional insulin.  But there is hope, there are others in the pipeline getting close to market - hopefully for you and the 3 others on Exubra it will be soon.  I believe there are also many small companies involved that would love $100 million in sales and might stick with it.  Although if long-term lung safety is not addressed, not sure if any will make it forever.

Good luck</description>
		<content:encoded><![CDATA[<p>Have you tried animal insulins.  I believe there might be someone on this site that will tell you Lilly forced Exubra off the market along with animal insulins years ago.  Blame Lilly.</p>
<p>But seriously, it is a shame this med was taken off the market - but that is the market economy we live in.  Pfizer spent billions and I believe they were selling about $20 million/qtr.  Pfizer is a big company, but no one can lose $1billion/year for a disease that is still treatable with traditional insulin.  But there is hope, there are others in the pipeline getting close to market - hopefully for you and the 3 others on Exubra it will be soon.  I believe there are also many small companies involved that would love $100 million in sales and might stick with it.  Although if long-term lung safety is not addressed, not sure if any will make it forever.</p>
<p>Good luck</p>
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		<title>By: Dennis Hodges</title>
		<link>http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-30641</link>
		<dc:creator>Dennis Hodges</dc:creator>
		<pubDate>Fri, 07 Dec 2007 21:27:02 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2007/11/inhaled-insulin-a-giant-step-for-mannkind/#comment-30641</guid>
		<description>Diabetes:  An American Epidemic

Let me start out by asking you this question.  

Is someone in your family a diabetic or do you know of someone that is a diabetic?  I will bet that everyone that reads this will answer YES to that question!

I have been a diabetic dependent on taking insulin shots for the past sixty years.  I have used about every type of insulin that has ever been put on the market plus I have used an insulin pump for a short time. I was taking four shots a day and after seeing an Exubera advertisement on TV I checked with my Doctor and he wrote a prescription for me to start using Exubera.

Exubra is the first diabetic treatment of its kind where you inhale the insulin into your mouth from the Exubera Inhaler instead of taking shots.  Type I and Type II diabetics can both use this medicine.

After sixty years of dealing with this disease I feel that Exubera is one of the most advanced, non-invasive methods ever devised for diabetics to take insulin.  This system gives diabetics a more realistic, normal life quality as opposed to taking shots everyday. It is a lot quicker to insert a blister into the inhaler and inhale it as opposed to getting out a syringe, filling it with insulin and giving yourself an injection.  

I was on Exubera for a short time and Pfizer Pharmaceutical sent me a letter announcing that it will no longer be making EXUBERA available to patients.

â€œ This decision was not based on any safety problems with Exubera.  Exubera is a safe and effective medicine and the feedback we have had from Exubera patients has been very positive.  However, Pfizer has made this decision because too few patients are taking Exubera and, since there are other medicines available that lower blood sugar, Pfizer will stop providing Exubera.â€

Making money and showing a profit is what companies are in business for,right? This product was on the market less than a year! 

It is my understanding that Bayer is investing a large sum of money into Pfizer for this new inhaled drug delivery system that will treat pulmonary disease, migraine headaches and antibiotics.  My question is:  Why get the cart ahead of the horse, if they already have a working system for insulin why force all of the people that are taking Exubera back to taking shots again?

In my opinion Exubera was the only product on the market that gave diabetics that small ray of hope to live a more normal life.</description>
		<content:encoded><![CDATA[<p>Diabetes:  An American Epidemic</p>
<p>Let me start out by asking you this question.  </p>
<p>Is someone in your family a diabetic or do you know of someone that is a diabetic?  I will bet that everyone that reads this will answer YES to that question!</p>
<p>I have been a diabetic dependent on taking insulin shots for the past sixty years.  I have used about every type of insulin that has ever been put on the market plus I have used an insulin pump for a short time. I was taking four shots a day and after seeing an Exubera advertisement on TV I checked with my Doctor and he wrote a prescription for me to start using Exubera.</p>
<p>Exubra is the first diabetic treatment of its kind where you inhale the insulin into your mouth from the Exubera Inhaler instead of taking shots.  Type I and Type II diabetics can both use this medicine.</p>
<p>After sixty years of dealing with this disease I feel that Exubera is one of the most advanced, non-invasive methods ever devised for diabetics to take insulin.  This system gives diabetics a more realistic, normal life quality as opposed to taking shots everyday. It is a lot quicker to insert a blister into the inhaler and inhale it as opposed to getting out a syringe, filling it with insulin and giving yourself an injection.  </p>
<p>I was on Exubera for a short time and Pfizer Pharmaceutical sent me a letter announcing that it will no longer be making EXUBERA available to patients.</p>
<p>â€œ This decision was not based on any safety problems with Exubera.  Exubera is a safe and effective medicine and the feedback we have had from Exubera patients has been very positive.  However, Pfizer has made this decision because too few patients are taking Exubera and, since there are other medicines available that lower blood sugar, Pfizer will stop providing Exubera.â€</p>
<p>Making money and showing a profit is what companies are in business for,right? This product was on the market less than a year! </p>
<p>It is my understanding that Bayer is investing a large sum of money into Pfizer for this new inhaled drug delivery system that will treat pulmonary disease, migraine headaches and antibiotics.  My question is:  Why get the cart ahead of the horse, if they already have a working system for insulin why force all of the people that are taking Exubera back to taking shots again?</p>
<p>In my opinion Exubera was the only product on the market that gave diabetics that small ray of hope to live a more normal life.</p>
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