Where Overseas FDA Inspections Took Place

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Since the beginning of the federal government’s fiscal year 2002, the FDA conducted approximately 1,379 inspections of foreign pharmaceutical facilities, often focused in countries with few reported quality concerns. The table below contains the number of inspections conducted by the FDA in the 10 countries with the highest number of pharmaceutical facilities inspected. Notice the number for China. (These numbers were provided by the FDA to the Senate Finance Committee).

Country 2002 2003 2004 2005 2006 2007 Total
India 10 19 36 33 34 61 193
Germany 23 14 35 25 20 18 135
Italy 16 31 25 21 17 12 122
Canada 27 12 17 22 24 16 118
U.K. 17 22 17 18 16 9 99
France 14 18 13 12 15 24 96
Japan 10 13 13 21 13 12 92
China 11 6 18 13 16 11 76
Switzerland 11 11 11 15 9 14 71
Ireland 11 5 12 14 2 7 51
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  1. It’s widely known that foreign inspections are primarily “pre-approval” inspections. So your inference that FDA inspects facilities in areas where quality is not typically an issue is wrong. Foreign inspectional assignments are merely responses to NDA/ANDA applications submitted by industry. Occasionally, there is the need for a “for cause” inspection, which is what we are sseing with heparin.

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