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	<title>Comments on: Expensive Placebos Work Better Than Cheap Ones</title>
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	<pubDate>Thu, 18 Mar 2010 23:50:05 +0000</pubDate>
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		<title>By: Bob Freeman</title>
		<link>http://www.pharmalot.com/2008/03/expensive-placebos-work-better-than-cheap-ones/#comment-190586</link>
		<dc:creator>Bob Freeman</dc:creator>
		<pubDate>Wed, 05 Mar 2008 16:11:34 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/expensive-placebos-work-better-than-cheap-ones/#comment-190586</guid>
		<description>Over many decades we have known the color of a tablet/capsule adds to the physician's and patient's perception of the drug and the illness.  For example, one wouldn't put a "trivial" color on a cancer drug, nor would you put a "somber" color on an antidepressant.

Given that many generics, especially those for drugs not in a commodity status, likely follow the dosage form design of the innovator's, it may be likely that cost is more important.</description>
		<content:encoded><![CDATA[<p>Over many decades we have known the color of a tablet/capsule adds to the physician&#8217;s and patient&#8217;s perception of the drug and the illness.  For example, one wouldn&#8217;t put a &#8220;trivial&#8221; color on a cancer drug, nor would you put a &#8220;somber&#8221; color on an antidepressant.</p>
<p>Given that many generics, especially those for drugs not in a commodity status, likely follow the dosage form design of the innovator&#8217;s, it may be likely that cost is more important.</p>
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		<title>By: Wissenswerkstatt &#124; Glaube kann Berge versetzen » Die suggestive Heilkraft von Medikamentenpreisen &#124; Werkstattnotiz LXXII</title>
		<link>http://www.pharmalot.com/2008/03/expensive-placebos-work-better-than-cheap-ones/#comment-190566</link>
		<dc:creator>Wissenswerkstatt &#124; Glaube kann Berge versetzen » Die suggestive Heilkraft von Medikamentenpreisen &#124; Werkstattnotiz LXXII</dc:creator>
		<pubDate>Wed, 05 Mar 2008 16:05:27 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/expensive-placebos-work-better-than-cheap-ones/#comment-190566</guid>
		<description>[...] im stets gut sortierten Blog von Ed Silverman finde ich soeben noch den Hinweis auf einen New York Times-Artikel von heute. Dort wird auch kurz skizziert, da&#223; es die [...]</description>
		<content:encoded><![CDATA[<p>[...] im stets gut sortierten Blog von Ed Silverman finde ich soeben noch den Hinweis auf einen New York Times-Artikel von heute. Dort wird auch kurz skizziert, da&#223; es die [...]</p>
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		<title>By: Justice in Michigan</title>
		<link>http://www.pharmalot.com/2008/03/expensive-placebos-work-better-than-cheap-ones/#comment-190547</link>
		<dc:creator>Justice in Michigan</dc:creator>
		<pubDate>Wed, 05 Mar 2008 16:00:24 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/expensive-placebos-work-better-than-cheap-ones/#comment-190547</guid>
		<description>This not news, but I think we need to be careful about overstating the link to dissatisfaction with generics.  Of course, there is a certain "something" about brand name.  And, especially lately, the assumption lingers that more generics are made in places less "kosher."  

Still, given the relatively liberal standards of bioequivalence, issues of fillers and dissolution time, etc., generics are demonstrably problematic in some instances, while in others they may actually be more efficacious.</description>
		<content:encoded><![CDATA[<p>This not news, but I think we need to be careful about overstating the link to dissatisfaction with generics.  Of course, there is a certain &#8220;something&#8221; about brand name.  And, especially lately, the assumption lingers that more generics are made in places less &#8220;kosher.&#8221;  </p>
<p>Still, given the relatively liberal standards of bioequivalence, issues of fillers and dissolution time, etc., generics are demonstrably problematic in some instances, while in others they may actually be more efficacious.</p>
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