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	<title>Comments on: Merck&#8217;s Singulair Tied To Suicide Reports</title>
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	<description>News, Comment and Conversation</description>
	<pubDate>Mon, 07 Jul 2008 03:38:48 +0000</pubDate>
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		<title>By: truthman30</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-306896</link>
		<dc:creator>truthman30</dc:creator>
		<pubDate>Tue, 22 Apr 2008 15:26:36 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-306896</guid>
		<description>To Nathan and HorusCat and all the other pharma indoctrinated people who comment here..

How do you think that depression manifests?..
How do you think that anxiety manifests?..
How do you think that Bipolar manifests?...
How do you think that OCD manifests?...

I really would like to know because you claim to have knowledge of these things and you continually promote drugs as effective treatments while also dismissing real patient experiences, real patient opinions and the eveidence which exists of the detrimental effects the drug treatments have had in the real world...

Depression is primarily an emotional disorder, there is nothing unnatural about it, it is a documented part of the human condition and experience which has been written about and expressed since the dawn of civilization...
There is no chemical imbalance , if there is any imbalance it is an emotional one, usually leaning on the negative side to the point of extreme unhappiness with the individuals perception of the world .. 
In many ways depression is a more insightful and compassionate view of the way the world actually is..
Yes, the world is painful, yes the world in unfair, yes life can be tough... these are hard truths 
Being high on a brain altering medicaton is an unnatural state of being and an unnatural response to a human experience... Peddling drug treatments for emotional experiences based on dubious and defunct scientific theories is fraud no matter what way you look at it..It is fraud ..

Anxiety is a natural response to stress or trauma, to claim that it is also a "mental disorder" is incorrect science ...
Anxiety and the fight or flight reaction are survival instincts and a nervous system in overdrive...
To peddle,encourage and push drug treatments as solutions to anxiety "disorders" is fraud...

OCD can manifest in many ways, usually stemming from insecurity , fear and neuorosis..
The only way it can be treated effectively without further damaging the individuals already fragile state is with compassion by a psychologist who needs to gently get to the root of the behaviour..
Encouraging drugs as treatment options for psychological problems is dangerous and is also Based on Fraud ...

Bipolar is also deeply psychological in nature with genetic and socio ecenomic factors, it can also manifest from a certain personality type, people who are prone to feel intense lows and intense highs as a reaction to their subjective experiences of the world and their lives.. 

Pushing drugs on people with personality types based on scientifically unproven psychiatric definitions is Fraud also...

There is no "NORMAL"... 
Medications which are marketed, designed and ultimately pushed on people who are deemed "abnormal" by a psychiatric-drug funded-drug cartel is fraudulant , opportunistic and exploititive of the human condition and experience...</description>
		<content:encoded><![CDATA[<p>To Nathan and HorusCat and all the other pharma indoctrinated people who comment here..</p>
<p>How do you think that depression manifests?..<br />
How do you think that anxiety manifests?..<br />
How do you think that Bipolar manifests?&#8230;<br />
How do you think that OCD manifests?&#8230;</p>
<p>I really would like to know because you claim to have knowledge of these things and you continually promote drugs as effective treatments while also dismissing real patient experiences, real patient opinions and the eveidence which exists of the detrimental effects the drug treatments have had in the real world&#8230;</p>
<p>Depression is primarily an emotional disorder, there is nothing unnatural about it, it is a documented part of the human condition and experience which has been written about and expressed since the dawn of civilization&#8230;<br />
There is no chemical imbalance , if there is any imbalance it is an emotional one, usually leaning on the negative side to the point of extreme unhappiness with the individuals perception of the world ..<br />
In many ways depression is a more insightful and compassionate view of the way the world actually is..<br />
Yes, the world is painful, yes the world in unfair, yes life can be tough&#8230; these are hard truths<br />
Being high on a brain altering medicaton is an unnatural state of being and an unnatural response to a human experience&#8230; Peddling drug treatments for emotional experiences based on dubious and defunct scientific theories is fraud no matter what way you look at it..It is fraud ..</p>
<p>Anxiety is a natural response to stress or trauma, to claim that it is also a &#8220;mental disorder&#8221; is incorrect science &#8230;<br />
Anxiety and the fight or flight reaction are survival instincts and a nervous system in overdrive&#8230;<br />
To peddle,encourage and push drug treatments as solutions to anxiety &#8220;disorders&#8221; is fraud&#8230;</p>
<p>OCD can manifest in many ways, usually stemming from insecurity , fear and neuorosis..<br />
The only way it can be treated effectively without further damaging the individuals already fragile state is with compassion by a psychologist who needs to gently get to the root of the behaviour..<br />
Encouraging drugs as treatment options for psychological problems is dangerous and is also Based on Fraud &#8230;</p>
<p>Bipolar is also deeply psychological in nature with genetic and socio ecenomic factors, it can also manifest from a certain personality type, people who are prone to feel intense lows and intense highs as a reaction to their subjective experiences of the world and their lives.. </p>
<p>Pushing drugs on people with personality types based on scientifically unproven psychiatric definitions is Fraud also&#8230;</p>
<p>There is no &#8220;NORMAL&#8221;&#8230;<br />
Medications which are marketed, designed and ultimately pushed on people who are deemed &#8220;abnormal&#8221; by a psychiatric-drug funded-drug cartel is fraudulant , opportunistic and exploititive of the human condition and experience&#8230;</p>
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		<title>By: Lisa R.</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-306817</link>
		<dc:creator>Lisa R.</dc:creator>
		<pubDate>Tue, 22 Apr 2008 14:59:41 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-306817</guid>
		<description>Hi,

I am prone to depression and I was taking Singulair for about 3 months.  I felt fine during that time, but I went off it a few weeks ago.  Since then, I've begun to enter a deep depression - one that I have never experienced before.  I started thinking things I would not normally think about like killing myself.  I started to not care how my friends or family would feel if I did this.  

I remembered reading an article while I was on Singulair linking it to suicidal thoughts and behavior.  I was happy that wasn't happening to me, but now I wonder if withdrawal from it is causing (or at least contributing to) my recent feelings. 

I have been on various medications from Singulair to antidepresssants to birth control.  I am finding more and more that you cannot trust these huge drug companies.  They only want money - that is ALL they are concerned with.  It's time to look towards herbs and natural remedies for for many of our ailments.  There are cultures who have used natural remedies and homeopathy for thousands of years and they are fine.  I am not swearing off western medicine, but I believe in so many cases of drugs, they do more harm than good.  You don't even know what the long-term effects are of so many of these drugs, especially those developed in the past 10-20 years.

The drug companies will keep on thriving unless people question their doctors and truly consider what drugs are absolutely necessary and what alternative they can use instead.</description>
		<content:encoded><![CDATA[<p>Hi,</p>
<p>I am prone to depression and I was taking Singulair for about 3 months.  I felt fine during that time, but I went off it a few weeks ago.  Since then, I&#8217;ve begun to enter a deep depression - one that I have never experienced before.  I started thinking things I would not normally think about like killing myself.  I started to not care how my friends or family would feel if I did this.  </p>
<p>I remembered reading an article while I was on Singulair linking it to suicidal thoughts and behavior.  I was happy that wasn&#8217;t happening to me, but now I wonder if withdrawal from it is causing (or at least contributing to) my recent feelings. </p>
<p>I have been on various medications from Singulair to antidepresssants to birth control.  I am finding more and more that you cannot trust these huge drug companies.  They only want money - that is ALL they are concerned with.  It&#8217;s time to look towards herbs and natural remedies for for many of our ailments.  There are cultures who have used natural remedies and homeopathy for thousands of years and they are fine.  I am not swearing off western medicine, but I believe in so many cases of drugs, they do more harm than good.  You don&#8217;t even know what the long-term effects are of so many of these drugs, especially those developed in the past 10-20 years.</p>
<p>The drug companies will keep on thriving unless people question their doctors and truly consider what drugs are absolutely necessary and what alternative they can use instead.</p>
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		<title>By: lila</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-272058</link>
		<dc:creator>lila</dc:creator>
		<pubDate>Thu, 10 Apr 2008 23:01:51 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-272058</guid>
		<description>A report from the Netherlands 2006 discusses depression. The report stated that in three cases the onset of the depression after taking Singulair was from 3-14 days.

Discussion and conclusion 
Lareb received four reports of depressive symptoms in patients using montelukast.Possible confounding includes that asthma itself has been associated with the development of depression . Inhalated corticosteroids can also exert effects on the central nervous system. Fluticason in combination with salmeterol which is used by patients A, B and D, is associated with hyperactivity and irritability whereas budesonide, which is used by patient C also has been associated with depression . 

The latency of montelukast-induced depressive symptoms varies from 3-14 days. 
 
In three of the cases a positive dechallenge was seen. The fact that the patients (except for one) did not suffer from depressive symptoms before they started montelukast, the short latency, and recovery after withdrawal of the drug all strengthen our hypothesis that depressive symptoms are an ADR (adverse drug reaction)related to the use of montelukast. 

According to the Marketing Authorisation Holder of montelukast, depression will be added to the product information.

http://www.lareb.nl/documents/kwb_2006_4_montel.pdf</description>
		<content:encoded><![CDATA[<p>A report from the Netherlands 2006 discusses depression. The report stated that in three cases the onset of the depression after taking Singulair was from 3-14 days.</p>
<p>Discussion and conclusion<br />
Lareb received four reports of depressive symptoms in patients using montelukast.Possible confounding includes that asthma itself has been associated with the development of depression . Inhalated corticosteroids can also exert effects on the central nervous system. Fluticason in combination with salmeterol which is used by patients A, B and D, is associated with hyperactivity and irritability whereas budesonide, which is used by patient C also has been associated with depression . </p>
<p>The latency of montelukast-induced depressive symptoms varies from 3-14 days. </p>
<p>In three of the cases a positive dechallenge was seen. The fact that the patients (except for one) did not suffer from depressive symptoms before they started montelukast, the short latency, and recovery after withdrawal of the drug all strengthen our hypothesis that depressive symptoms are an ADR (adverse drug reaction)related to the use of montelukast. </p>
<p>According to the Marketing Authorisation Holder of montelukast, depression will be added to the product information.</p>
<p><a href="http://www.lareb.nl/documents/kwb_2006_4_montel.pdf" rel="nofollow">http://www.lareb.nl/documents/kwb_2006_4_montel.pdf</a></p>
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		<title>By: HorusCat</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231738</link>
		<dc:creator>HorusCat</dc:creator>
		<pubDate>Fri, 28 Mar 2008 13:41:27 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231738</guid>
		<description>And "whatever"...I sometimes thank God I only have boys...although they bring their own set of issues.  

Lisa,
I used to suffer from an eating disorder--and I got the idea from a friend of mine, who told me about it.  You don't hear much anymore about eating disorders...I don't think the problem has gone away, though.</description>
		<content:encoded><![CDATA[<p>And &#8220;whatever&#8221;&#8230;I sometimes thank God I only have boys&#8230;although they bring their own set of issues.  </p>
<p>Lisa,<br />
I used to suffer from an eating disorder&#8211;and I got the idea from a friend of mine, who told me about it.  You don&#8217;t hear much anymore about eating disorders&#8230;I don&#8217;t think the problem has gone away, though.</p>
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		<title>By: Lisa Van S</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231722</link>
		<dc:creator>Lisa Van S</dc:creator>
		<pubDate>Fri, 28 Mar 2008 13:31:44 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231722</guid>
		<description>Nathan,

"Please",... remember that hormone-filled adolescents, are not mentally ill, they are actually quite normal. I suggest you get a pair of ear plugs,..stomping feet and slamming doors will become a daily ritual.</description>
		<content:encoded><![CDATA[<p>Nathan,</p>
<p>&#8220;Please&#8221;,&#8230; remember that hormone-filled adolescents, are not mentally ill, they are actually quite normal. I suggest you get a pair of ear plugs,..stomping feet and slamming doors will become a daily ritual.</p>
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		<title>By: Lisa Van S</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231707</link>
		<dc:creator>Lisa Van S</dc:creator>
		<pubDate>Fri, 28 Mar 2008 13:26:14 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231707</guid>
		<description>Horus,

Websites on eating disorders and suicide is a huge problem,..no doubt about that!!!!!</description>
		<content:encoded><![CDATA[<p>Horus,</p>
<p>Websites on eating disorders and suicide is a huge problem,..no doubt about that!!!!!</p>
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		<title>By: Lisa Van S</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231701</link>
		<dc:creator>Lisa Van S</dc:creator>
		<pubDate>Fri, 28 Mar 2008 13:23:51 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231701</guid>
		<description>Nathan,

Actually it is the opposite,..Teens dont want to take medication because theyve been told they have a chemical imbalance of the brain. Teens, especially girls!, are receptive to counseling, as long as the counselor is "their choice", and not the choice of another. Teens are huge on the trust issue.</description>
		<content:encoded><![CDATA[<p>Nathan,</p>
<p>Actually it is the opposite,..Teens dont want to take medication because theyve been told they have a chemical imbalance of the brain. Teens, especially girls!, are receptive to counseling, as long as the counselor is &#8220;their choice&#8221;, and not the choice of another. Teens are huge on the trust issue.</p>
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		<title>By: HorusCat</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231700</link>
		<dc:creator>HorusCat</dc:creator>
		<pubDate>Fri, 28 Mar 2008 13:23:45 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231700</guid>
		<description>Nathan and Lisa,

Kind of off on a tangent, but there is a town in Wales that is suffering from a sort of suicide epidemic.  It appears that the kids are sort of egging each other on...although that's not quite the way to explain it.  Perhaps this phenomenon among teens is one way to explain why teen suicide is higher in densely populated areas...to a certain extent, it is "contagious," in that teens get the idea from hearing about it.  Eating disorders, especially bulimia, are passed from one teen to another--that is, one girl hears about it from another and decides to try it.  

It makes you wish you could lock your teenager up until their frontal lobes mature.</description>
		<content:encoded><![CDATA[<p>Nathan and Lisa,</p>
<p>Kind of off on a tangent, but there is a town in Wales that is suffering from a sort of suicide epidemic.  It appears that the kids are sort of egging each other on&#8230;although that&#8217;s not quite the way to explain it.  Perhaps this phenomenon among teens is one way to explain why teen suicide is higher in densely populated areas&#8230;to a certain extent, it is &#8220;contagious,&#8221; in that teens get the idea from hearing about it.  Eating disorders, especially bulimia, are passed from one teen to another&#8211;that is, one girl hears about it from another and decides to try it.  </p>
<p>It makes you wish you could lock your teenager up until their frontal lobes mature.</p>
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		<title>By: Lisa Van S</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231676</link>
		<dc:creator>Lisa Van S</dc:creator>
		<pubDate>Fri, 28 Mar 2008 13:16:54 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231676</guid>
		<description>Nathan,

You will just have to trust me on this one.
This is why raw data is so crucial,... the data should be placed in the public domaine.</description>
		<content:encoded><![CDATA[<p>Nathan,</p>
<p>You will just have to trust me on this one.<br />
This is why raw data is so crucial,&#8230; the data should be placed in the public domaine.</p>
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		<title>By: Nathan</title>
		<link>http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231674</link>
		<dc:creator>Nathan</dc:creator>
		<pubDate>Fri, 28 Mar 2008 13:16:23 +0000</pubDate>
		<guid isPermaLink="false">http://www.pharmalot.com/2008/03/mercks-singulair-tied-to-suicide-reports/#comment-231674</guid>
		<description>Lisa,
My kids are quite young -- but thinking to the future I found it interesting that compared to other age groups, adolescents are more likely to commit suicide immediately after a tramatic event.  Also I found it interesting that suicide rates have been continuously dropping for the last 15 years -- which is consistant with other reports I've seen.  Also interesting that adolescent suicide rates are higher in densely populated areas whereas elderly suidide rates are higher in rural areas.  I don't know what exactly the make of it, but it's interesting.

I also found a quote from Horus's article quite interesting (against thinking about when my girls become teenagers): "Teenagers are often resistant to psychotherapy, and unlike adults, who can quit a job or leave a marriage that might be aggravating their unhappiness, adolescents are almost always stuck with their lots."

I never thought of it that way.  If I get depressed, there is usually something I can *do* about it.  (ie change my circumstances)  Until my kids get out of high school, they are pretty much stuck.  I'll try to remember that in 10 or 15 years when I'm dealing with hormone-filled emotional teenage girls in my home!</description>
		<content:encoded><![CDATA[<p>Lisa,<br />
My kids are quite young &#8212; but thinking to the future I found it interesting that compared to other age groups, adolescents are more likely to commit suicide immediately after a tramatic event.  Also I found it interesting that suicide rates have been continuously dropping for the last 15 years &#8212; which is consistant with other reports I&#8217;ve seen.  Also interesting that adolescent suicide rates are higher in densely populated areas whereas elderly suidide rates are higher in rural areas.  I don&#8217;t know what exactly the make of it, but it&#8217;s interesting.</p>
<p>I also found a quote from Horus&#8217;s article quite interesting (against thinking about when my girls become teenagers): &#8220;Teenagers are often resistant to psychotherapy, and unlike adults, who can quit a job or leave a marriage that might be aggravating their unhappiness, adolescents are almost always stuck with their lots.&#8221;</p>
<p>I never thought of it that way.  If I get depressed, there is usually something I can *do* about it.  (ie change my circumstances)  Until my kids get out of high school, they are pretty much stuck.  I&#8217;ll try to remember that in 10 or 15 years when I&#8217;m dealing with hormone-filled emotional teenage girls in my home!</p>
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