Comments on: The Clot Thickens: Lilly’s Prasugrel Performs Well http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/ News, Comment and Conversation Fri, 10 Feb 2012 21:06:29 +0000 http://wordpress.org/?v=2.6.2 By: HorusCat http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-238568 HorusCat Mon, 31 Mar 2008 21:45:02 +0000 http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-238568 nipsey, Careful, you'll get sat on hard with that kind of talk! (I know, I've been there; I'm still squashed.) nipsey,
Careful, you’ll get sat on hard with that kind of talk! (I know, I’ve been there; I’m still squashed.)

]]> By: nipsey russell http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-238194 nipsey russell Mon, 31 Mar 2008 17:11:39 +0000 http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-238194 lauren, what ARE you doing on a blog called pharmalot? arent there tin foil hat forums aimed more at your crowd? lauren, what ARE you doing on a blog called pharmalot? arent there tin foil hat forums aimed more at your crowd?

]]> By: Pharma News 3_29 « Impactiviti blog http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-237711 Pharma News 3_29 « Impactiviti blog Mon, 31 Mar 2008 11:39:58 +0000 http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-237711 [...] according to a stent analysis from the head-to-head TRITON-TIMI 38 trial…more. And, more here from [...] [...] according to a stent analysis from the head-to-head TRITON-TIMI 38 trial…more. And, more here from [...]

]]> By: Doc http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-236688 Doc Mon, 31 Mar 2008 02:17:08 +0000 http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-236688 It is a scam alright, lots of talk about big relative risk reductions, but little on bleeding - hmmmmmm. It is a scam alright, lots of talk about big relative risk reductions, but little on bleeding - hmmmmmm.

]]> By: Scam Spotter http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-236507 Scam Spotter Sun, 30 Mar 2008 23:30:31 +0000 http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-236507 This was not new data. The stent thrombosis data was rehashed because Lilly sees it as a desperate way to up the risk/reward decision. Prasugrel massively increases the risk for death and serious bleeding. So Lilly is using this new serious problem cause by stents as a niche market where the benefit might outweigh the risk. The comparator was Plavix at too low a dose so that gave prasugrel this inflated efficacy. This was not new data. The stent thrombosis data was rehashed because Lilly sees it as a desperate way to up the risk/reward decision. Prasugrel massively increases the risk for death and serious bleeding. So Lilly is using this new serious problem cause by stents as a niche market where the benefit might outweigh the risk. The comparator was Plavix at too low a dose so that gave prasugrel this inflated efficacy.

]]> By: Lauren http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-236141 Lauren Sun, 30 Mar 2008 19:14:48 +0000 http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-236141 Don't hold your breath waiting for me to ever take a Lilly drug. Or any drug, if I could possibly help it. Drugs kill, and people like Lilly execs don't tell. They hide the side effects, doctor the clinical trial, and put pablum articles in medical journals. No thanks. Don’t hold your breath waiting for me to ever take a Lilly drug. Or any drug, if I could possibly help it. Drugs kill, and people like Lilly execs don’t tell. They hide the side effects, doctor the clinical trial, and put pablum articles in medical journals.

No thanks.

]]> By: CV MD http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-234463 CV MD Sat, 29 Mar 2008 22:20:03 +0000 http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-234463 I believe that these results are very good for prasugrel and could signal some real difficulty for Plavix. Although Plavix has done quite well on the market, it does not provide the degree or the consistency of prasugrel. The FDA also appears to be impressed if they are putting the review on the fast track. I think that once the companies sort out the groups that handle the drug somewhat differently and add this additional information to the database, they should be in good shape. I believe that these results are very good for prasugrel and could signal some real difficulty for Plavix. Although Plavix has done quite well on the market, it does not provide the degree or the consistency of prasugrel. The FDA also appears to be impressed if they are putting the review on the fast track. I think that once the companies sort out the groups that handle the drug somewhat differently and add this additional information to the database, they should be in good shape.

]]> By: Doc http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-234438 Doc Sat, 29 Mar 2008 21:59:21 +0000 http://www.pharmalot.com/2008/03/the-clot-thickens-lillys-prasugrel-performs-well/#comment-234438 I'll take the fewer heart attacks and you can have the increased major bleeding, that sounds fair. Now the question is, how do you identify those two populations, so you use the correct antiplatelet in each? I’ll take the fewer heart attacks and you can have the increased major bleeding, that sounds fair. Now the question is, how do you identify those two populations, so you use the correct antiplatelet in each?

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