Wyeth And Elan Suspend Alzheimer’s Trial

Make a comment

thumbsdown2.jpgThe drugmakers say that a mid-stage clinical trial of an Alzheimer’s vaccine has been suspended while they look into a potentially serious side effect suffered by one patient in the study, Reuters reports. Dosing in the study of the experimental vaccine, ACC-001, was halted after the patient was hospitalized with skin lesions from what the physician serving as lead researcher suspected was a case of inflammation of blood vessels.

“Following discussion with the FDA, all further dosing has been suspended while this particular event is fully evaluated,” Jonathan Birt, an Elan spokesman, tells Reuters. The drugmakers are in talks with health regulators and the physician to further understand the clinical and scientific issues, Birt adds.

The patient, meanwhile, has been released from the hospital and the lesions are healing, he says. Elan, though, stresses the vaccine and study has no connection to bapineuzumab, its lead Alzheimer’s drug candidate, which is also being developed with Wyeth and is in late-stage clinical testing.

Jump to comments

Share

Leave a Comment

Subscribe

RSS Feed

Comments feed for this post only.

Clear

Clear

© 2007- 2008 Newark Morning Ledger Co.  All Rights Reserved.

Thanks for trying out the new Pharmalot printing tools. If you're got any suggestions for how we can help you print better, please let us know by clicking on the contact link at http://www.pharmalot.com/