Comments on: Boehringer Blows Up Two Drugs In One Trial http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/ News, Comment and Conversation Fri, 10 Feb 2012 20:29:57 +0000 http://wordpress.org/?v=2.6.2 By: Bruce http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-365340 Bruce Thu, 03 Jul 2008 05:06:51 +0000 http://www.pharmalot.com/?p=13668#comment-365340 Guess the results were bad after all. The news is they are eliminating 50% of their sales force assigned to sell Aggrenox to neurologists! Poof! You're done. Guess the results were bad after all. The news is they are eliminating 50% of their sales force assigned to sell Aggrenox to neurologists! Poof! You’re done.

]]> By: Bruce http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-357026 Bruce Mon, 19 May 2008 20:39:11 +0000 http://www.pharmalot.com/?p=13668#comment-357026 I think a picture of the Hindenburg torching would be somehow more appropriate as this is one "fine and upstanding" imperial German Reich. Just a thought. As for the outsiders, this is not such an upstanding company. Those inside know the dirt and the brooms cannot sweep fast enough. I think a picture of the Hindenburg torching would be somehow more appropriate as this is one “fine and upstanding” imperial German Reich. Just a thought. As for the outsiders, this is not such an upstanding company. Those inside know the dirt and the brooms cannot sweep fast enough.

]]> By: Ed Silverman http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-356992 Ed Silverman Mon, 19 May 2008 13:50:05 +0000 http://www.pharmalot.com/?p=13668#comment-356992 Hi Jack2, Actually, the site has a rather large number, and percentage, of readers/viewers from industry and outfits that work with, or support, pharma. I know because I see the subscriber sign-up lists. However, many people apparently refrain from diving into the discussions here because they worry about their jobs and don't even wish to use an anonymous sign-on name. I have been told this repeatedly in private conversations. Consumers who show up presumably don't have the same constraints, self-imposed or otherwise. And of course, this is the Internet, where anyone can and does show up. Hopefully, these visits and participation can make for a richer discussion. As a result, though, the impression you may have of the visitors can be a bit skewed, at least depending upon such variables as the topic being discussed. Cheers ed Hi Jack2,

Actually, the site has a rather large number, and percentage, of readers/viewers from industry and outfits that work with, or support, pharma. I know because I see the subscriber sign-up lists.

However, many people apparently refrain from diving into the discussions here because they worry about their jobs and don’t even wish to use an anonymous sign-on name. I have been told this repeatedly in private conversations.

Consumers who show up presumably don’t have the same constraints, self-imposed or otherwise. And of course, this is the Internet, where anyone can and does show up.

Hopefully, these visits and participation can make for a richer discussion. As a result, though, the impression you may have of the visitors can be a bit skewed, at least depending upon such variables as the topic being discussed.

Cheers
ed

]]> By: Jack2 http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-356991 Jack2 Mon, 19 May 2008 13:26:30 +0000 http://www.pharmalot.com/?p=13668#comment-356991 HC, 20% of people will always like you and 20% of people will never like you. This website draws richly from the latter 20%. HC, 20% of people will always like you and 20% of people will never like you. This website draws richly from the latter 20%.

]]> By: HorusCat http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-356929 HorusCat Sat, 17 May 2008 01:50:02 +0000 http://www.pharmalot.com/?p=13668#comment-356929 Retrospective analysis of various blogs and posts on this site reveals the following: For most of those on this site, no matter what the drug companies do, they are wrong. p<.0000001 Retrospective analysis of various blogs and posts on this site reveals the following:

For most of those on this site, no matter what the drug companies do, they are wrong.

p<.0000001

]]> By: Doc http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-356920 Doc Sat, 17 May 2008 00:40:05 +0000 http://www.pharmalot.com/?p=13668#comment-356920 To say that BI deserves kudos for releasing the ProFess trial results is like saying that the presidential candidates deserve kudos for releasing their tax returns. They had no option. BI has had their sales force pumping this trial for years as the final answer to show Aggrenox is better than Plavix in secondary stroke reduction. They have consistently mislead MDs on the MATCH and CHARISMA trial results, in regard to Plavix. (see their reprint carrier number (07/07) AG46470). Sorry, they deserve no credit, except they did the trial - reporting results was not a magnanomous gesture of open honest data revelation. To say that BI deserves kudos for releasing the ProFess trial results is like saying that the presidential candidates deserve kudos for releasing their tax returns. They had no option. BI has had their sales force pumping this trial for years as the final answer to show Aggrenox is better than Plavix in secondary stroke reduction. They have consistently mislead MDs on the MATCH and CHARISMA trial results, in regard to Plavix. (see their reprint carrier number (07/07) AG46470). Sorry, they deserve no credit, except they did the trial - reporting results was not a magnanomous gesture of open honest data revelation.

]]> By: Bruce http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-356915 Bruce Fri, 16 May 2008 23:05:03 +0000 http://www.pharmalot.com/?p=13668#comment-356915 Flushing with an Ace? What are you talking about? Hack is about right. Paging Spin Doctor You are needed in the PR Dept for a massive German Pharma House Flushing with an Ace? What are you talking about? Hack is about right.

Paging Spin Doctor

You are needed in the PR Dept for a massive German Pharma House

]]> By: pharma PR hack http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-356913 pharma PR hack Fri, 16 May 2008 21:41:20 +0000 http://www.pharmalot.com/?p=13668#comment-356913 On Target did show the ACE and ARB substantially the same outcome with the one difference being the lack of flushing with micardis. But did not show an ACE and ARB equal better together versus seperate which might actually be a wake up call to physicians that in most cases poly pharmacy doesn't equal better. Granted, the argument has been made that it is the same info as the Valeant trial earlier but that was a hospitalized heart failure patient population versus the typical cardiology patient patient in On Target, Transcend and Profess. Overall, this does not bode well for BI's growth plans for micardis and definitely doesn't do any service for aggrenox. On Target did show the ACE and ARB substantially the same outcome with the one difference being the lack of flushing with micardis. But did not show an ACE and ARB equal better together versus seperate which might actually be a wake up call to physicians that in most cases poly pharmacy doesn’t equal better.
Granted, the argument has been made that it is the same info as the Valeant trial earlier but that was a hospitalized heart failure patient population versus the typical cardiology patient patient in On Target, Transcend and Profess. Overall, this does not bode well for BI’s growth plans for micardis and definitely doesn’t do any service for aggrenox.

]]> By: Chris http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-356912 Chris Fri, 16 May 2008 21:37:03 +0000 http://www.pharmalot.com/?p=13668#comment-356912 How else should BI have behaved? They had a very big disppointment, disclosed the results and accepted they are poor and now will have to deal with the consequences. I don't think this reveals especially great integrity nor does it reflect any wrongdoing on the part of the marketers - I'm not sure where that one came from. I suppose it was handled better than the ENHANCE study though. How else should BI have behaved? They had a very big disppointment, disclosed the results and accepted they are poor and now will have to deal with the consequences. I don’t think this reveals especially great integrity nor does it reflect any wrongdoing on the part of the marketers - I’m not sure where that one came from. I suppose it was handled better than the ENHANCE study though.

]]> By: Bruce http://www.pharmalot.com/2008/05/boehringer-blows-up-two-drugs-in-one-trial/#comment-356911 Bruce Fri, 16 May 2008 21:26:46 +0000 http://www.pharmalot.com/?p=13668#comment-356911 To associate high integrity based upon the fact that they released these awful results is missing the point. That is like comparing two pickpocket artists and saying one is a better person because he did not run from the police when they arrived to arrest him. Seems like its time to come to Daddy for these marketeers. Maybe they can now go somewhere else and sell their version of 'sunshine'to another sucker. See how many press releases there were for this data versus how they talked it up. To associate high integrity based upon the fact that they released these awful results is missing the point. That is like comparing two pickpocket artists and saying one is a better person because he did not run from the police when they arrived to arrest him. Seems like its time to come to Daddy for these marketeers. Maybe they can now go somewhere else and sell their version of ’sunshine’to another sucker.

See how many press releases there were for this data versus how they talked it up.

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