I believe I got Peyronies last December through trauma caused by intercourse when my wife was on top and moving quickly which caused my penis to come out and she sat on it and I heard a crack.

Shortly after ( a week I think) I noticed a distortion in my penis.

In the last 6 months the distortion has caused my penis to bend to the right at 15 degrees and go soft at the end and finally reduce in size by about 3 cms.

The reason I am describing the detail above is to show the damage that is Peyronies disease and is mainly caused through sexual activity trauma plus probably a genetic link.

Every since I got my “problem” it has seriously effected me emotionally and I feel less of a man with no future.

Sex with my wife is difficult and I always feel inadequate at the conclusion.

It has a devastating effect and is definitely NO joke.

I hope Xiaflex works because I believe many more men have Peyronies then is revealed in the statistics.

The disease is a MAJOR issue for MEN which has been seriously neglected in the past by the medical profession.

Thanks, but don’t worry, I come from the no autopsy/no foul playground. I didn’t mean to whine, or come off as scolding. I honestly don’t think you can research, think, or otherwise ponder this ailment without some sort of humor entering the picture. As the saying goes, it could be worse…

You raise good points and we shouldn’t make fun of someone’s affliction. Having suffered from mental illness I know what it’s like to be made fun of publicly when you have an identifable illness, especially one that’s socially acceptable to make fun of and to use as a means of discrimination. I mean just look at this and many other blogs and how people here and even politicians use mental illness as an invective.

As for numbers of sufferers of Peyronie’s I simply don’t know what the true numbers are and I doubt anyone really does.

My own joke regarding cottage cheese thighs was not meant to show any disrepect to those with Peyronie’s or even those with cellulite since people are self conscious about that. It was only to indicate that I suspect that the true market lies elsewhere as it’s easy to visualize these other markets, they’re potentially much larger, and as this is a common marketing and development tactic for drug companies. If I offended anyone inadvertantly I’m sorry.

I think we should take your example and all stand up here and not allow any ridiculing of illnesses or disabilities and especially not when it’s used to attack and silence adversaries.

Salmon

Still, decision to embark upon an injectable treatment option would require lots of thought.

It is painful and it must complicate aiming the stream. Similarly to ED, the symptoms of which Viagra aids, it can affect marital relations adversely.

It might even be useful for cottage cheese thighs.

Now that would be real money.

Where’s my broker’s number?

As for the US component, it may not be an orphan designation but it probably would be a fast-track approval. Plus many countries use approval in the US or EU as the basis for approval in their country. Whether it’s the US or EU typically depends on where the product is manufactured with approval in the country of manufacture being critical. Since this is a US based company a US approval would probably be of interest to PFE since many of the countries they may want to market it in would likely need a US approval first. Since this is this company’s first product anything that lowers the regulatory hurdles would be useful.