Comments on: Glaxo Loses Bid To Preempt Paxil Lawsuit

By: Elaine

Elaine — Thu, 17 Jun 2010 18:58:20 +0000

This reaction to SSRI’s is the scariest reaction. The words “jittery” or “akathisia” or “restless” don’t properly describe what happens. Maybe the words, “someone jumping out from behind a door a thousands times,” more properly describes it. Imagine all of your feelings of despair suddenly turn into feelings of happiness at the thought of your own death. Terrifying. Mental paralysis. I was lucky–I was able to call a suicide hotline. Some people are not so lucky.

Paxil is not alone. Zoloft does it too. Why not restrict prescribing to psychiatrists? They restricted accutane to the dermatologists.

To be fair to the drug companies, the whackos on the bus (public) also elicit mental paralysis (over time), but that’s another story.

May God bless Tricia Mason.

By: Kelly

Kelly — Sun, 30 May 2010 02:43:51 +0000

Paxil is not an “evil drug.” It’s very true that it can have bad side effects and dependency, but if you do your research, so do many other antidepressants of its type. There’s really no magical antidepressant that works for everyone and is totally safe. There are terrible cases with loads of them. I have panic disorder and did a lot of research before going on any medication because I was very worried about side effects and dependency, and what I found is that I’m not really safe no matter what drug I’m on. And for those of you who would respond that I shouldn’t be taking one, I’ll just say now that I was unable to be reasoned with without it.

By: Jeff

Jeff — Wed, 14 Apr 2010 03:50:44 +0000

Paxil is an evil drug, and if everyone weren’t addicted to this hell spawn drug, it should be taken off the market.

And after they PROVED that evidence was originally suppressed for its approval, why do they keep approving it for more things???

By: Lisa Van Syckel

Lisa Van Syckel — Tue, 16 Mar 2010 12:43:48 +0000

Truthman, Check out today’s Miami Herald. A psychiatrist over medicated fostercare children with psychtropic drugs in clinical trials. Will definitely make you sick to your stomach

By: truthman30

truthman30 — Tue, 16 Mar 2010 12:23:33 +0000

Why is Paxil still on the market? ..
GSK has paid over 1 Billion in lawsuits claiming damage from the drug, yet it’s still on the market and it’s still being prescribed!
What does it take to have a drug banned? If causing suicides, homicides and birth defects can all be attributed to one drug, then surely this is enough negatives to get it pulled!! Can anyone explain to me why Paxil is still on the market as a product? Surely, any product that causes this much damage to people should not be offered as an option for anything!

Check out Seroxat (Paxil) secrets for the whole story of this horrible drug ..

http://seroxatsecrets.wordpress.com/

By: Pharmadev

Pharmadev — Mon, 01 Mar 2010 11:55:53 +0000

Ok, time for a dose of reality.
As a developer you invest many years and many, millions on development with FDA overseeing every step. You spend 1-2 years negotiating labels and then more years and millions on watching for side effects (and yes FDA was intensely studying suicide issues in these drug to decide if changing the label would do more harm than good).

Now if you do everything right as a company by FDA you still can be destroyed by any jury of folks with no undersanding of medicine of phamaceutils/decides and an elected judge with a different opinion in the hundreds of counties accross the country.

Good luck to anyone that expects companies to take on innovative products in complex disease like depression. Look at what the companies are doing now … Movng to generics; OTC; anmal health and other lower risk areas.

By: annonymous

annonymous — Sun, 28 Feb 2010 23:19:09 +0000

From what I’ve read, Paxil has certain characteristics that explain some of the nasty clinical side effects seen from it. IIRC, it has very short half life.

That explains why it is perhaps among the most addictive of the SSRIs, with something like 25% of those who take it developing physical dependence. (That when they discontinue, they experience serious withdrawal side effects).

Additionally, it has among the higher rates of sexual dysfunction and other side effects.

Not to mention a variety of other troublesome pharamcokinetics, like including the ability to make Tamoxifen, a breast cancer treatment, not work as well.

That said, it has become extremely popular. Why? Cynics might point towards the rise of generalized anxiety disorder, a recent and suddenly very popular condition that - perhaps by cosmic coincidence - Paxil was shown to be a solid treatment for.

I decided to go anonymous for this because it is my heartfelt belief that Paxil is a seriously flawed medication that highlights the serious shortcomings of the SSRIs - and is used when there are significantly safer options.

Chalk another victory for the power of Big Pharma, to make an extremely questionable medication extremely popular.

The only people who suffer are those who, say, start taking it and commit suicide several days later (stories of which I have encountered in my research.)

By: JaT

JaT — Sun, 28 Feb 2010 21:57:58 +0000

I have to disagree with you, Lisa and Pharmavet, unless I am missing something.

As with doctors offices- pharma reps peddle their wares to nurse practitioners. So if we are relying on sales reps to further the educations of doctors, there is no reason to think that a nurse practitioner has any less product information.
It is the drug, not the prescriber, at issue, I think. Nobody giving the class of drugs enough consideration.

Hmmm?

By: Justice in MI

Justice in MI — Sun, 28 Feb 2010 03:40:57 +0000

Thanks, Lisa. Their lawyer in the case is quoted: “”Pre-emption in prescription drugs is a relic of the past.”

Certainly nowhere near being true in Michigan!

By: Lisa Van Syckel

Lisa Van Syckel — Sun, 28 Feb 2010 00:29:52 +0000

Justice, That last link is no good, try this one

http://www.baumhedlundlaw.com/drug2_press/mason_preemption.php